A common problem in security is deciding how to scan PCs that are suspected to be infected with a computer virus.
One approach is to use anti-virus software already installed on the PC, however mistrust of that anti-virus software may be wise considering that there exist a number of viruses that disable or alter anti-virus software. An alternative approach is to boot the computer from some other media (CDROM, Floppy Disk, USB Mass Storage, PXE) and run an anti-virus program from that media. This approach increases the trustworthiness of the the anti-virus software but brings up the question of how to ensure that the latest anti-virus definitions are available.
Knoppix is a bootable linux distribution that comes with Clam Anti-virus and support the downloading of anti-virus definitions to a ramdisk. Thus, you can boot from the CDROM which has a complete read-only operating system installed already and then run the included virus-scanner which will get the latest virus updates over the net. This provides you with a safe and easy method to initially respond to suspected infections.
Knoppix can be obtained by direct download from a number of mirror sites or via BitTorrent.